Patient FAQ

pharmacogenomics

Pharmacogenomic testing, also known as medication response testing, identifies how genes affect a person's response to drugs. It combines pharmacology (the science of drugs) with genomics (the study of genes and their functions) to determine effective, safe medications and doses tailored to a person's genetic makeup. Learn more about PHARMACOGENOMICS.

THE ONEOME RIGHTMED® COMPREHENSIVE TEST

Medications affect everyone differently. Some people metabolize drugs more quickly and others much more slowly, resulting in different responses to medications. This creates a challenge for doctors when trying to choose the right medication and dose for each patient. In addition, some individuals may have mild to severe side effects from medications. The OneOme RightMed comprehensive test informs your doctor on how your body may respond to medications, which helps them to make more informed prescription decisions.

The RightMed test is not the "end all be all" answer. There are other factors that contribute to how you may respond to a medication aside from genetics (e.g., allergic reaction, immune response, intolerance to inactive ingredients, health factors, drug-drug interactions, environmental factors, other medical conditions, etc.). Administration of any medication requires careful therapeutic monitoring by a qualified healthcare professional. Your doctor remains ultimately responsible for all of your diagnosis and treatment decisions.

The OneOme RightMed comprehensive test is a doctor-ordered pharmacogenomic test intended to help you and your healthcare provider understand how you may respond to certain medications based on your genetics. It does not cover ancestry, cosmetic features, or similar information that may be provided by certain direct-to-consumer tests. Although the RightMed test is not intended to diagnose any hereditary disease or disease risk, OneOme will report secondary findings for certain genetic results that you and your doctor may wish to discuss.

The actionable reports that OneOme provides to your doctor may help him/her to better select which medications to prescribe. Since your DNA does not change, the test results can be used by your doctors for medication decisions for years to come.

GETTING THE ONEOME RIGHTMED® COMPREHENSIVE TEST

There are two ways to get the RightMed test:

  1. You can buy the test online. Fill out this form to buy your test. A physician from an independent network will review your information and order the test for you (U.S. only; eligibility restrictions may apply). LEARN MORE about this option.
  2. You can get the test from your doctor. Download our PATIENT TOOLKIT to get familiar with the test. Then bring the provider materials and order form from this toolkit to your next doctor appointment to discuss whether the test is right for you.

When ordered by your doctor, the cost of the RightMed test includes sample collection (through either a cheek swab kit that can be mailed to your home or performed at your doctor's office, or a blood sample), pharmacogenomic testing services, data analysis, clinical interpretation, the RightMed comprehensive test report, and several reporting options for your doctor.

When you purchase the test online, you’ll receive everything listed above, plus additional services. The services include a DNA sample kit shipped to your home, a review of your order and test results by an independent physician, and a consult with a board-certified genetic counselor to review your results. Eligibility restrictions may apply. LEARN MORE >

When ordered by your doctor, OneOme offers its RightMed comprehensive test in all U.S. states, except New York, and in select international locations. In the near future, OneOme plans to expand availability to New York and other international areas.

When you purchase the test online, the test and provider services are only available to individuals in the United States, excluding those who reside in New York.

For more information on availability within your area, please CONTACT US.

No. Your genetic information does not change, so once you and your doctor(s) have the test results, the information can be used for years to come.

OneOme reserves the right to cancel an order when any of the following occurs:

  1. OneOme does not receive a sample within 45 days of the sample's collection date or of the kit's delivery date
  2. OneOme does not receive payment within 45 days of the order date (for patient self-pay orders)
  3. OneOme does not receive required information within 45 days of the order date
PURCHASING A RIGHTMED COMPREHENSIVE TEST ONLINE (U.S. only)

You can learn about this option and purchase your RightMed test on our BUY A TEST page. This option is only available in the U.S. only and other eligibility restrictions may apply.

Here’s how it works:

  1. Fill out THIS FORM to purchase the test.
  2. Once the kit is shipped to you, perform a simple cheek swab. Activate your kit online, then mail it back. An independent physician will review your information and order your test.
  3. Once your sample is processed and your results are ready, you will be contacted to schedule a 30-minute phone session with a board-certified genetic counselor to receive and discuss your results.
  4. Share your RightMed test report with your doctors so they can use it as part of your care, both now and in the future.

The cost is $349, which includes the RightMed test and provider services (independent physician review and a consult with a genetic counselor to review your results). It can be paid for with a credit card, health saving account (HSA) card, or PayPal.

For $349, the RightMed test and provider services include:

  • A DNA sample test kit shipped for free to your home, with prepaid return shipping
  • A review of your order and test results by a physician from an independent network
  • Your RightMed comprehensive test report, covering hundreds of medications, which may help guide your doctors' medication decisions for years to come
  • A phone or video consultation, scheduled at your convenience, with a board-certified genetic counselor to review your results and answer any questions

While most individuals are eligible to receive a RightMed test with these services, there are some individuals who are not. You will not be eligible for a RightMed test through the provider network if you:

  • Are under 18 years of age
  • Reside in New York or outside of the United States
  • Have had a liver, bone marrow, or stem cell transplant
  • Are currently experiencing kidney or liver failure

The independent provider services, including the physician review and the genetic counselor consult, are provided by PWN. You can reach them by calling 888-494-7333.

Genetic counselors are healthcare professionals with specialized training in medical genetics and counseling. They help patients understand how genetics plays a role in their health.

During your consult, the genetic counselor will explain what pharmacogenomic testing is, review your results with you, and answer any questions you have.

No. Neither OneOme nor PWN (the independent provider network) can provide medical advice or make changes to your medication regimen. Your own doctor or healthcare provider is best suited to make prescription changes for you if they are needed. You will receive a copy of your RightMed comprehensive test report to share with your doctors. Your doctors can then incorporate the results into your care. Do not make any changes to your medications without consulting your doctor.

Once you’ve purchased a RightMed test, OneOme will ship out a DNA sample collection via two-day shipping within 1-2 business days. After you activate and send back your kit, your results will be ready within 9-12 business days (approximately two weeks) of OneOme receiving your sample. At that time, you'll receive an email to schedule a consult with a genetic counselor to discuss your results.

You'll receive your results electronically once your consult has been scheduled.

Yes. When you fill out the purchase form, you have the option to specify that we send the test kit to someone other than yourself.

Note: Gift recipients must fall with our eligibility requirements. Recipients are not eligible for the RightMed test if they:

  • Are under 18 years of age
  • Reside in New York or outside of the United States
  • Have had a liver, bone marrow, or stem cell transplant
  • Have had kidney or liver failure
ONEOME SAMPLE KIT

Yes, OneOme can ship test kits to P.O. boxes in most states and U.S. territories.

Once your kit has been shipped, you will receive an email with a tracking number so you can monitor the arrival date. If your kit does not arrive within 7 days, please CONTACT US, and we will address this right away.

Contact us, and we will work with you to address this issue.

The kit you will receive to collect your sample includes simple, step-by-step instructions on how to complete the simple cheek swab. You can also watch a demonstration video showing you how to provide your sample.

Contact us to let us know what happened when providing your sample. We can discuss options and next steps.

We encourage you to send in your sample as soon as you have activated your kit. This will ensure that your test results are returned as quickly as possible.

If collecting your sample at home, it is important to activate your kit either online or by calling (844)-663-6635 before mailing back your sample to OneOme. Activation is required before we can process your sample at the OneOme lab. You will need the barcode number located on the tube to activate your kit.

If you collected your sample at home, your kit must be activated before we can begin processing your sample in the OneOme lab. Please contact us to activate your kit. If we receive your sample and it has not been activated we will contact you to complete the activation step.

MY RESULTS

Although your genetic information does not change, what we know about it (how we interpret it) may change. OneOme routinely updates its database as new information about pharmacogenomics becomes available to the scientific community. A “regenerated” report is one that contains updated information based on what we've learned since the original report was generated. The “original” report still remains on file with us.

We encourage you to contact your doctor to discuss any updated information in your regenerated report. As always, do not make any changes to your medications or treatment plan without first talking to your doctor.

While infrequent, OneOme sometimes adds new genes to the RightMed test. If you or your doctor would like these additional genes or alleles to be added to your results, you must be tested again.

OneOme regularly adds new medications to the RightMed test. OneOme automatically regenerates your report at no extra cost to include new medications, assuming the genes and alleles associated with the medications were on our panel when you were tested.

If, however, the genes or alleles associated with the new medications were not on our panel when you were tested, they will not be included on regenerated reports. If you or your doctor would like these newly added medications to be added to your results, you must be tested again.

BILLING

OneOme offers a few different payment options depending upon how the test was ordered. For more information visit our BILLING INFORMATION.

When your doctor orders the test:

  • Patient self-pay price (U.S. only): The cost is $349 when paid directly by the patient and not billed to insurance.
  • Insurance billed price (U.S. only): OneOme can work with your insurance company to determine whether it will cover any portion of the cost of the test and what the cost would be if billed through your plan. If your out-of-pocket cost is estimated to be less than or equal to OneOme's self-pay price, OneOme will submit the claim to the insurance plan. If your out-of-pocket cost is estimated to exceed OneOme’s self-pay price, OneOme will reach out to discuss options. Your provider may also choose to bill insurance on your behalf.
  • Institutional billed price: For all patients outside the U.S., and any patient in the U.S. not using patient self-pay or insurance billing, pricing is determined by the healthcare institution from which you receive the test.

When you purchase the test online (U.S. only):

  • The cost is $349, which includes the test plus the services provided by an independent provider network. The services include the ordering of the test and a consult with a board-certified genetic counselor to review your results. Insurance billing is not available.

OneOme accepts payment from all major credit cards, health savings accounts (HSAs), and PayPal.

When ordered by your doctor, OneOme tests are reimbursed by some private insurance plans within the U.S. Our goal is to allow you to access the lowest estimated payment option available. We review your insurance information and assess your payment options prior to testing, using your deductible, co-insurance, and health plan details. If you qualify for OneOme's Financial Assistance Program or your out-of-pocket cost is estimated to be $249 or lower, OneOme will submit the claim to your insurance plan. If your out-of-pocket cost is estimated to exceed $249, OneOme will reach out to discuss other options.

Note: Insurance billing is not available for tests purchased online.

For orders placed in the U.S. by your doctor, you can choose to have OneOme bill your insurance at the time of the order. Insurance billing is not available for tests purchased online.

OneOme accepts all Medicare and Medicaid plans. If you have a traditional Medicare/Medicaid or Managed Medicaid Plan, your cost will be $0. Medicare Advantage Plans may have a co-payment or deductible requirement.

You will need to provide your doctor with both sides of your insurance card(s), your member ID number, your group number, and your relationship to the primary policyholder. Some insurance companies may also require additional authorization forms or other documentation.

In most cases OneOme can change the payment option for an order up until the report has been sent to the ordering healthcare provider.

Yes, HSAs can be used to pay for tests via the patient self-pay option or when paying a balance from insurance billing.

Preauthorization does not guarantee payment. Insurance companies determine how much they will pay and what charges will be billed to the patient after a medical claim is filed. The patient is responsible for any portion of the test fee not covered by the insurance company for any reason including, but not limited to, copayments, co-insurance, unmet deductibles, or non-covered services.

Note: The patient is responsible for remitting any funds received directly from the insurance company to OneOme.

If OneOme has not yet received your sample and you decide that you no longer want the test, you can receive a refund on the purchasing card. We are unable to process a refund once our lab has received your sample and the processing has begun.

SECURITY AND PRIVACY

Your genetic information contains sensitive information about you. For example, from a test that analyzes your genome, you can learn information about your likelihood of developing certain diseases, your ethnicity, your relatives, your carrier status, and your response to drugs. (Note: OneOme’s test predicts your response to drugs. Although our test is not intended to diagnose any hereditary disease or risk, we will report secondary findings for certain genetic results, so that you have an opportunity to discuss these findings with your doctor.)

In addition, the genome itself is a unique identifier for you — no one else has the same one as you. While there are clear clinical benefits to genetic testing, it also introduces new risks to patient privacy, and patients are potentially vulnerable to the misuse of their genetic information. While there are laws that protect patients from health insurance companies and employers using genetic information to discriminate against them, there are still concerns about the use of genetic information to discriminate against applicants for life and disability insurance. For this reason, it’s important that you only work with companies that are committed to safeguarding your genetic information.

At OneOme, we recognize that you have entrusted us to keep your data safe and secure. To accomplish this we have implemented strict policies, processes, and technologies along with identifying a data security and privacy officer who ensures we maintain a high level of data security. We take great strides to have rigorous security standards in order to handle your genomic information with great care. To learn more, please consult our PRIVACY POLICY.

Laws and policies have been developed and passed to protect the privacy and security of your genomic information. In 2008, Congress passed the Genetic Information Nondiscrimination Act (GINA) to restrict health insurance companies and employers from accessing an individual’s genetic information, as well as to prohibit genetic discrimination. The passage of GINA makes it illegal for health insurers or employers to request or require genetic information of an individual or of any family members. Additionally, some states have even more comprehensive laws than GINA. Learn more about GINA.

In addition to GINA, there is the Health Insurance Portability and Accountability Act of 1996 (HIPAA). HIPAA protects patient privacy by restricting the sharing of your medical information. The HIPAA Privacy Rule establishes protections to maintain the confidentiality of patients' individually identifiable health information. This information is called Protected Health Information (PHI) and includes things like your name, address, and social security number. There are limits on when and with whom OneOme may share PHI. To learn more go to ONEOME NOTICE OF PRIVACY PRACTICES.

The primary focus of the OneOme RightMed comprehensive test is to provide your doctor with information on how your DNA may affect your response to drugs. OneOme's tests are not intended to provide information about disease predisposition, paternal status, ethnicity, hereditary, or ancestry information. However, OneOme will report secondary findings for certain genetic results so that you have an opportunity to discuss these additional findings with your doctor. To learn more about this, please consult our TERMS OF SERVICE.

OneOme keeps your DNA sample for up to 60 days from the date your report is released to your doctor. This is for the purpose of quality assurance and in case your doctor orders follow up testing.

View OneOme’s PRIVACY POLICY. In general, except as described in our privacy policy, we do not disclose HIPAA protected patient information to third parties without the patient’s consent.

GINA, the Genetic Information Nondiscrimination Act (passed in 2008), prohibits medical insurance companies and employers from discriminating against individuals on the basis of genetic information, including the OneOme RightMed PGx test results.

HIPAA, the Health Insurance Portability and Accountability Act of 1996, governs how protected health information (PHI) is used, processed, transmitted and/or maintained. OneOme’s website, portal, and systems are compliant with HIPAA requirements, which means that all patient-specific information is encrypted and safe. Patient information is only made available to individuals who require access to perform the OneOme test, provide services, and generate the results.