Patient FAQ

pharmacogenomics
What is pharmacogenomic (PGx) testing?

Pharmacogenomic testing, also known as medication response testing, identifies how genes affect a person's response to drugs. It combines pharmacology (the science of drugs) with genomics (the study of genes and their functions) to determine effective, safe medications and doses tailored to a person's genetic makeup. Learn more about PHARMACOGENOMICS.

THE ONEOME RIGHTMED® COMPREHENSIVE TEST
Why would I need this test?

Medications affect everyone differently. Some people metabolize drugs more quickly and others much more slowly, resulting in different responses to medications. This creates a challenge for doctors when trying to choose the right medication and dose for each patient. In addition, some individuals may have mild to severe side effects from medications. The OneOme RightMed comprehensive test informs your doctor on how your body may respond to medications, which helps them to make more informed prescription decisions.

Will this test tell me all the information I need to know about which medications will work for me?

The RightMed test is not the "end all be all" answer. There are other factors that contribute to how you may respond to a medication aside from genetics (e.g., allergic reaction, immune response, intolerance to inactive ingredients, health factors, drug-drug interactions, environmental factors, other medical conditions, etc.). Administration of any medication requires careful therapeutic monitoring by a qualified healthcare professional. Your doctor remains ultimately responsible for all of your diagnosis and treatment decisions.

What is the difference between this test and other genetic tests (e.g., 23andme)?

The OneOme RightMed comprehensive test is a doctor-ordered pharmacogenomic test intended to help you and your healthcare provider understand how you may respond to certain medications based on your genetics. It does not cover ancestry, cosmetic features, or similar information that may be provided by certain direct-to-consumer tests. Although the RightMed test is not intended to diagnose any hereditary disease or disease risk, OneOme will report secondary findings for certain genetic results that you and your doctor may wish to discuss.

How will my doctor use the information provided by the OneOme RightMed test?

The actionable reports that OneOme provides to your doctor may help him/her to better select which medications to prescribe. Since your DNA does not change, the test results can be used by your doctors for medication decisions for years to come.

GETTING THE ONEOME RIGHTMED® COMPREHENSIVE TEST
How can I get the RightMed comprehensive test?

There are two ways to get the RightMed test:

  1. Your doctor can order it. For more information on how to talk to your doctor about the test, download our PATIENT TOOLKIT.
  2. You can REQUEST A TEST. A physician from an independent network will review your test request to determine if the test is right for you, and if approved, order the test for you (eligibility restrictions may apply). LEARN MORE about this option.
What is included in the cost of the RightMed comprehensive test?

When ordered by your doctor, the cost of the RightMed test includes sample collection (through either a cheek swab kit that can be mailed to your home or performed at your doctor's office, or a blood sample), pharmacogenomic testing services, data analysis, clinical interpretation, the RightMed comprehensive test report, and several reporting options for your doctor.

When the RightMed test is requested online by the independent provider network, you’ll receive everything listed above, plus additional services. The services include a review of your request by a physician to determine if the test is right for you, ordering of approved tests, and a consult with a board-certified genetic counselor to review your results. For test requests that are not approved, the requester will be notified and will not be charged for the test or services. Eligibility restrictions may apply. LEARN MORE >

Where is the RightMed comprehensive test available?

When ordered by your doctor, OneOme offers its RightMed comprehensive test in all U.S. states, except New York, and in select international locations. In the near future, OneOme plans to expand availability to New York and other international areas.

For tests requested online through the independent provider network, the test and provider services are only available to individuals in the United States, excluding those who reside in New York, New Jersey, and Rhode Island.

For more information on availability within your area, please CONTACT US.

Do I need to be retested if I change doctors or go to a different type of doctor?

No. Your genetic information does not change, so once you and your doctor(s) have the test results, the information can be used for years to come.

REQUESTING A RIGHTMED COMPREHENSIVE TEST (through the independent provider network)
How do I request a RightMed test (through the independent provider network) and how does it work?

You can learn about this option and request a RightMed test on our REQUEST A TEST page.

Here’s how it works:

  1. Fill out our REQUEST FORM.
  2. A physician from an independent provider network will review your request and evaluate whether the test is right for you.
  3. If your request is approved, OneOme will reach out to you via email for payment ($349, payable by credit card or HSA card). If for any reason your request is not approved, we will contact you with other options.
  4. After OneOme receives your payment, we will send you a DNA sample collection kit. Perform a simple cheek swab, then mail it back using the postage paid return label.
  5. Once your sample is processed and your results are ready, you will be contacted to schedule a 30-minute phone session with a board-certified genetic counselor to receive and discuss your results.
  6. Share your RightMed test report with your doctors so they can use it as part of your care, both now and in the future.
How much does it cost?

The cost is $349, which includes the RightMed test and provider services (independent physician review and a consult with a genetic counselor to review your results). It can be paid for with a credit card or health saving account (HSA).

What is included in the cost?

If your test request is approved, you’ll receive the RightMed test and provider services for $349 (payable by credit card or HSA accounts). Here is what’s included:

  • A review of your test order and test results by a physician from an independent network
  • A DNA sample test kit shipped to your home, with prepaid return shipping
  • A phone or video consultation, scheduled at your convenience, with a board-certified genetic counselor to review your results and answer any questions
  • Your RightMed comprehensive test report, covering hundreds of medications, which may help guide your doctors’ medication decisions for years to come
Am I eligible to receive a RightMed test with provider services?

While anyone can request a RightMed test, some individuals may not be approved. For some patients, especially those with complex health issues, your own doctor may be best suited to order the RightMed test for you and to ensure the results are properly incorporated into your care.

You will likely not be eligible for a RightMed test through the provider network if you:

  • Are under 18 years of age
  • Are over 75 years of age and taking medication(s)
  • Reside outside of the United States
  • Reside in Rhode Island, New Jersey, or New York
  • Have had a stem cell or liver transplant
  • Have had specific kidney or liver problems
  • Have certain types of complex medication regimens
Who provides the independent provider services and how do I contact them?

The independent provider services, including the physician review and the genetic counselor consult, are provided by PWN. You can reach them by calling 888-494-7333.

What is a genetic counselor and what is covered during the genetic counselor consult?

Genetic counselors are healthcare professionals with specialized training in medical genetics and counseling. They help patients understand how genetics plays a role in their health.

During your consult, the genetic counselor will explain what pharmacogenomic testing is, review your results with you, and answer any questions you have.

Will any changes be made to my prescriptions through this service?

No. Neither OneOme nor PWN (the independent provider network) can provide medical advice or make changes to your medication regimen. Your own doctor or healthcare provider is best suited to make prescription changes for you if they are needed. You will receive a copy of your RightMed comprehensive test report to share with your doctors. Your doctors can then incorporate the results into your care. Do not make any changes to your medications without consulting your doctor.

When will I get my results?

Once OneOme receives your request, it will typically be reviewed within 2-3 business days by an independent physician to determine if the test is right for you. OneOme will notify you via email once your request is reviewed and collect payment from you if your request is approved.

Once payment is received, OneOme will ship a DNA sample collection kit to you. You’ll collect your sample and ship the kit back using the postage paid return label. Once OneOme receives your sample, it will take approximately four days for the sample to be processed. Once your sample is processed and your results are ready, you’ll receive an email with a link to schedule a consult with a genetic counselor. Your results will then be shared with you during or after the consult.

ONEOME RIGHTMED SAMPLE KIT
Can OneOme send a test kit to a P.O. box?

Yes, OneOme can ship test kits to P.O. boxes in most states and U.S. territories.

When will my OneOme kit arrive?

Once your kit has been shipped, you will receive an email with a tracking number so you can monitor the arrival date. If your kit does not arrive within 7 days, please CONTACT US, and we will address this right away.

What do I do if I never received my kit?

Contact us, and we will work with you to address this issue.

How do I provide my sample?

The kit you will receive to collect your sample includes simple, step-by-step instructions on how to complete the simple cheek swab. You can also watch a demonstration video showing you how to provide your sample.

What should I do if I make a mistake when providing my sample?

Contact us to let us know what happened when providing your sample. We can discuss options and next steps.

How quickly do I need to return my sample?

We encourage you to send in your sample as soon as you have activated your kit. This will ensure that your test results are returned as quickly as possible.

How do I activate my kit?

If collecting your sample at home, it is important to activate your kit either online or by calling (844)-663-6635 before mailing back your sample to OneOme. Activation is required before we can process your sample at the OneOme lab. You will need the barcode number located on the tube to activate your kit.

What should I do if I forgot to activate my kit before mailing it back to OneOme?

If you collected your sample at home, your kit must be activated before we can begin processing your sample in the OneOme lab. Please contact us to activate your kit. If we receive your sample and it has not been activated we will contact you to complete the activation step.

MY RESULTS
I have a “regenerated” report that looks different than my “original” report. Why has my report changed?

Although your genetic information does not change, what we know about it (how we interpret it) may change. OneOme routinely updates its database as new information about pharmacogenomics becomes available to the scientific community. A “regenerated” report is one that contains updated annotations and other information based on what we learn. The “original” report is the report of record, which remains on file with us.

We encourage you to contact your doctor to discuss any updated information in your regenerated report. As always, do not make any changes to your medications or treatment plan without first talking to your doctor.

If additional genes are added to the test, are they also added to my results?

While infrequent, OneOme sometimes adds new genes to the RightMed test. If you or your doctor would like these additional genes or alleles to be added to your results, you must be tested again. Since OneOme does not store DNA samples, your doctor must place a new order, and you must provide a new DNA sample for OneOme to generate a new report with the added genes. You or your clinic will then be charged for the current price of the RightMed test.

BILLING
How much does the RightMed comprehensive test cost?

OneOme offers a few different payment options depending upon how the test was ordered. For more information visit our BILLING INFORMATION.

When the test is ordered by your doctor:

  • Patient self-pay price: The cost is $349 when paid directly by the patient and not billed to insurance.
  • Insurance billed price: For patients in the U.S., OneOme can work with your insurance company to determine whether it will cover any portion of the cost of the test and what the cost would be if billed through your plan. If your out-of-pocket cost is estimated to be less than or equal to OneOme's self-pay price, OneOme will submit the claim to the insurance plan. If your out-of-pocket cost is estimated to exceed OneOme’s self-pay price, OneOme will reach out to discuss options.

When the test is requested online (through the independent provider network):

  • The cost is $349, which includes the test plus the services provided by an independent provider network. The services include a review of your request by a physician to determine if the test is right for you, ordering of test (for approved requests), and a consult with a board-certified genetic counselor to review your results. Insurance billing is not available.

OneOme accepts payment from all major credit cards, health savings accounts (HSAs), and PayPal.

Is this test covered by insurance?

The RightMed test, when ordered by your doctor, is reimbursed by some private insurance plans. Our goal is to allow you to access the lowest estimated payment option available. We review your insurance information and assess your payment options prior to testing, using your deductible, co-insurance, and health plan details. If your out-of-pocket cost is estimated to be less than or equal to OneOme's self-pay price ($349), OneOme will submit the claim to your insurance plan. If your out-of-pocket cost is estimated to exceeds OneOme’s self-pay price, OneOme will reach out to discuss options.

Note: Insurance billing is not available for tests requested online through the independent provider network.

Can you bill my insurance?

For orders placed by your doctor, you can choose to have OneOme bill your insurance at the time of the order for the RightMed test. Insurance billing is not available for tests requested online through the independent provider network.

I’m on Medicaid or Medicare; what are my options?

OneOme accepts all Medicare and Medicaid plans. If you have a traditional Medicare/Medicaid or Managed Medicaid Plan, your cost will be $0. Medicare Advantage Plans may have a co-payment or deductible requirement.

What information do I need to provide for you to bill insurance?

You will need to provide your doctor with both sides of your insurance card(s), your member ID number, your group number, and your relationship to the primary policyholder. Some insurance companies may also require additional authorization forms or other documentation.

Can the payment option be changed once the order is placed?

In most cases OneOme can change the payment option for an order up until the report has been sent to the ordering healthcare provider.

Can I use my health savings account (HSA) to pay for a RightMed test?

Yes, HSAs can be used to pay for the RightMed test via the patient self-pay option or when paying a balance from insurance billing.

Why did I receive an invoice for charges (partial or total) after my insurance was verified and preauthorization was obtained?

Preauthorization does not guarantee payment. Insurance companies determine how much they will pay and what charges will be billed to the patient after a medical claim is filed. The patient is responsible for any portion of the test fee not covered by the insurance company for any reason including, but not limited to, copayments, co-insurance, unmet deductibles, or non-covered services.

Note: The patient is responsible for remitting any funds received directly from the insurance company to OneOme.

What is OneOme's refund policy?

If OneOme has not yet received your sample and you decide that you no longer want the RightMed test, you can receive a refund on the purchasing card. We are unable to process a refund once our lab has received your sample and the processing has begun.

SECURITY AND PRIVACY
What risks to my privacy does getting a genetic test pose?

Your genetic information contains sensitive information about you. For example, from a test that analyzes your genome, you can learn information about your likelihood of developing certain diseases, your ethnicity, your relatives, your carrier status, and your response to drugs. (Note: OneOme’s test predicts your response to drugs. Although our test is not intended to diagnose any hereditary disease or risk, we will report secondary findings for certain genetic results, so that you have an opportunity to discuss these findings with your doctor.)

In addition, the genome itself is a unique identifier for you — no one else has the same one as you. While there are clear clinical benefits to genetic testing, it also introduces new risks to patient privacy, and patients are potentially vulnerable to the misuse of their genetic information. While there are laws that protect patients from health insurance companies and employers using genetic information to discriminate against them, there are still concerns about the use of genetic information to discriminate against applicants for life and disability insurance. For this reason, it’s important that you only work with companies that are committed to safeguarding your genetic information.

How does OneOme protect my information?

At OneOme, we recognize that you have entrusted us to keep your data safe and secure. To accomplish this we have implemented strict policies, processes, and technologies along with identifying a data security and privacy officer who ensures we maintain a high level of data security. We take great strides to have rigorous security standards in order to handle your genomic information with great care. To learn more, please consult our PRIVACY POLICY.

What laws exist that protect my information?

Laws and policies have been developed and passed to protect the privacy and security of your genomic information. In 2008, Congress passed the Genetic Information Nondiscrimination Act (GINA) to restrict health insurance companies and employers from accessing an individual’s genetic information, as well as to prohibit genetic discrimination. The passage of GINA makes it illegal for health insurers or employers to request or require genetic information of an individual or of any family members. Additionally, some states have even more comprehensive laws than GINA. Learn more about GINA.

In addition to GINA, there is the Health Insurance Portability and Accountability Act of 1996 (HIPAA). HIPAA protects patient privacy by restricting the sharing of your medical information. The HIPAA Privacy Rule establishes protections to maintain the confidentiality of patients' individually identifiable health information. This information is called Protected Health Information (PHI) and includes things like your name, address, and social security number. There are limits on when and with whom OneOme may share PHI. To learn more go to YOUR HEALTH INFORMATION PRIVACY RIGHTS.

What information does OneOme report to my doctor?

The primary focus of the OneOme RightMed test is to provide your doctor with information on how your DNA may affect your response to drugs. The OneOme RightMed comprehensive test is not intended to provide information about disease predisposition, paternal status, ethnicity, hereditary, or ancestry information. However, OneOme will report secondary findings for certain genetic results so that you have an opportunity to discuss these additional findings with your doctor. To learn more about this, please consult our TERMS OF SERVICE.

What does OneOme do with my DNA sample once the report is sent to my doctor?

OneOme keeps your DNA sample for up to 60 days from the date your report is released to your doctor. This is for the purpose of quality assurance and in case your doctor orders follow up testing.

What is OneOme's privacy policy?

View OneOme’s PRIVACY POLICY. In general, except as described in our privacy policy, we do not disclose HIPAA protected patient information to third parties without the patient’s consent.

What is GINA?

GINA, the Genetic Information Nondiscrimination Act (passed in 2008), prohibits medical insurance companies and employers from discriminating against individuals on the basis of genetic information, including the OneOme RightMed PGx test results.

What is HIPAA?

HIPAA, the Health Insurance Portability and Accountability Act of 1996, governs how protected health information (PHI) is used, processed, transmitted and/or maintained. OneOme’s website, portal, and systems are compliant with HIPAA requirements, which means that all patient-specific information is encrypted and safe. Patient information is only made available to individuals who require access to perform the OneOme test, provide services, and generate the results.