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RightMed comprehensive test

The RightMed® comprehensive test is a medication response test (also known as a pharmacogenomic test) that analyzes an individual's DNA to determine how he or she may respond to hundreds of medications. By predicting which medications may — or may not — work best for each individual, the RightMed test may lead to more effective prescriptions, fewer side effects, and less trial and error to find the right medication.

Test details

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MEDICATIONS

The RightMed comprehensive test covers hundreds of commonly prescribed medications, including omeprazole (Prilosec), simvastatin (Zocor), citalopram (Celexa), clopidogrel (Plavix), warfarin (Coumadin), codeine, morphine, alprazolam (Xanax), phenytoin (Dilantin), metoprolol (Lopressor), plus many more.


View complete medication list >

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MEDICAL CONDITIONS

The RightMed comprehensive test covers medications used for many medical conditions.

    • Acute migraine
    • ADHD
    • Allergies
    • Alzheimer's disease
    • Anticoagulation
    • Antiplatelet therapy
    • Anxiety
    • Arrhythmias
    • Bacterial infection
    • Benign prostatic
      hyperplasia
    • Cancer
    • Chronic hepatitis C
    • Depression
    • Diabetes
    • Dyslipidemia
    • Fungal infection
    • Gastroesophageal
      reflux disease
    • Gout
    • HIV infection
    • Hypertension
    • Immunosuppression
    • Migraine prophylaxis
    • Overactive bladder
    • Pain
    • Parkinson's disease
    • Psychosis
    • Rheumatoid arthritis
    • Seizures
    • Sleep disorders
    • Smoking cessation

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GENES

The RightMed comprehensive test analyzes genes involved in drug metabolism, drug targets, drug receptors, and drug transporters. Analysis is provided for genes that have been shown, based on OneOme's rigorous research and standards for inclusion, to affect how a patient responds to many commonly prescribed medications.

CYP1A2*1C, *1D, *1E, *1F, *1J, *1K, *1L, *1V, *1WToggle icon

rs12720461NM_000761.4:c.-10+113C>T

rs2069514NG_008431.2:g.28338G>A

rs2069526NM_000761.4:c.-10+103T>G

rs35694136NM_000761.4:c.-1635delT

rs762551NM_000761.4:c.-9-154C>A

CYP2B6*4, *5, *6, *7, *9, *16, *18Toggle icon

rs2279343NM_000767.4:c.785A>G

rs28399499NM_000767.4:c.983T>C

rs3211371NM_000767.4:c.1459C>T

rs3745274NM_000767.4:c.516G>T

CYP2C ClusterG/AToggle icon

rs12777823NC_000010.10:g.96405502G>A

CYP2C9*2, *3, *4, *5, *6, *8, *11Toggle icon

rs1057910NM_000771.3:c.1075A>C

rs1057911NM_000771.3:c.1425A>T

rs1799853NM_000771.3:c.430C>T

rs28371685NM_000771.3:c.1003C>T

rs28371686NM_000771.3:c.1080C>G

rs56165452NM_000771.3:c.1076T>C

rs7900194NM_000771.3:c.449G>A

rs9332131NM_000771.3:c.817delA

CYP2C19*2, *3, *4, *4B, *10, *17Toggle icon

rs12248560NM_000769.2:c.-806C>T

rs28399504NM_000769.2:c.1A>G

rs4244285NM_000769.2:c.681G>A

rs4986893NM_000769.2:c.636G>A

rs6413438NM_000769.2:c.680C>T

CYP2D6*2A, *2, *3, *4, *4N, *4M, *5, *6, *6C, *7, *8, *9, *10, *11, *12, *13, *14A, *14B, *15, *17, *18, *19, *29, *31, *34, *35, *36, *39, *41, *42, *59, *63, *64, *68, *69, *70, *91, *109Toggle icon

hCV32407220 (rs765776661)NM_000106.5:c.1411_1412insTGCCCACTG

rs1065852NM_000106.5:c.100C>T

rs1080985NM_000106.5:c.-1584C>G

rs1135840NM_000106.5:c.1457G>C

rs16947NM_000106.5:c.886C>T

rs201377835NM_000106.5:c.181-1G>C

rs267608319NM_000106.5:c.1319G>A

rs28371706NM_000106.5:c.320C>T

rs28371725NM_000106.5:c.985+39G>A

rs35742686NM_000106.5:c.775delA

rs3892097NM_000106.5:c.506-1G>A

rs5030655NM_000106.5:c.454delT

rs5030656NM_000106.5:c.841_843delAAG

rs5030862NM_000106.5:c.124G>A

rs5030865NM_000106.5:c.505G>A

rs5030867NM_000106.5:c.971A>C

rs59421388NM_000106.5:c.1012G>A

rs72549346NM_000106.5:c.1088_1089insGT

rs72549353NM_000106.5:c.765_768delAACT

rs769258NM_000106.5:c.31G>A

rs774671100NM_000106.5:c.137_138insT

rs79292917NM_000106.5:c.975G>A

CYP3A4*1B, *22Toggle icon

rs2740574NM_017460.5:c.-392G>A

rs35599367NM_017460.5:c.522-191C>T

CYP3A5*3, *6, *7Toggle icon

rs10264272NM_000777.4:c.624G>A

rs41303343NM_000777.4:c.1035_1036insT

rs776746NM_000777.4:c.219-237G>A

CYP4F2*3Toggle icon

rs2108622NM_001082.4:c.1297G>A

COMTVal158MetToggle icon

rs4680NM_000754.3:c.472G>A

DPYD*2A (1905+1G>A, IVS14+1G>A), Asp949Val, *13Toggle icon

rs3918290NM_000110.3:c.1905+1G>A

rs55886062NM_000110.3:c.1679T>G

rs67376798NM_000110.3:c.2846A>T

DRD2Promoter variant -241A>GToggle icon

rs1799978NM_000795.3:c.-585A>G

F220210G>AToggle icon

rs1799963NM_000506.4:c.*97G>A

F5Arg534Gln (Leiden, 1691G>A)Toggle icon

rs6025NM_000130.4:c.1601G>A

GRIK4Non-coding (intronic) T>C variantToggle icon

rs1954787NM_001282470.2:c.83-10039T>C

HLA-AHLA-A*31:01Toggle icon

HLA00097NM_002116 (interrogated at exon 2)

HLA-BHLA-B*15:02, HLA-B*57:01, HLA-B*58:01Toggle icon

HLA00386NM_005514 (interrogated at exon 2 and intron 2)

HLA00381NM_005514 (interrogated at exon 3)

rs144012689NM_005514.7:c.1012+104A>T

HTR2AIntron 2, T>C variantToggle icon

rs7997012NM_000621.4:c.614-2211T>C

HTR2CPromoter variant -759C>TToggle icon

rs3813929NM_000868.3:c.-759C>T

IL28B (IFNL4)Non-coding (intronic) C>T variantToggle icon

rs12979860NM_001276254.2:c.151-152G>A

MTHFR677C>T; 1298A>CToggle icon

rs1801133NM_005957.4:c.665C>T

rs1801131NM_005957.4:c.1286A>C

NUDT15Arg139CysToggle icon

rs116855232NM_018283.3:c.415C>T

OPRM1Asn40Asp; 118A>GToggle icon

rs1799971NM_000914.4:c.118A>G

SLC6A4c.-1810A>G; -1791_-1749del43Toggle icon

rs25531NM_001045.5:c-1936A>G

rs774676466NM_001045.5:c.-1917_-1875del43

SLCO1B1*5, *17, *21Toggle icon

rs4149015NM_006446.4:c.-910G>A

rs4149056NM_006446.4:c.521T>C

rs2306283NM_006446.4:c.388A>G

TPMT*2, *3A, *3B, *3C, *4Toggle icon

rs1142345NM_000367.3:c.719A>G

rs1800460NM_000367.3:c.460G>A

rs1800462NM_000367.3:c.238G>C

rs1800584NM_000367.3:c.626-1G>A

UGT1A1*6, *28 (TA7)Toggle icon

rs1976391NM_001072.3:c.862-9697A>G

rs4148323NM_001072.3:c.862-6536G>A

VKORC1Promoter variant -1639G>AToggle icon

rs9923231NM_001311311.1:c.-1639G>A

rs7200749NM_001311311.1:c.442C>T

MTHFR is available for providers to order as an optional, complimentary add-on to the RightMed comprehensive test. MTHFR is not available to patients who purchase the test online.

Learn more about these genes, including their impact on medication response and any guidelines associated with them.

RightMed comprehensive test report

Test results are presented in the RightMed comprehensive test report, which categorizes medications into a simple, easy-to-read format:

  • high risk icon
    MAJOR
    GENE-DRUG
       INTERACTION   

  • medium risk icon
    MODERATE
    GENE-DRUG
       INTERACTION   

  • low risk icon
    MINIMAL
    GENE-DRUG
       INTERACTION   

Given that a patient's DNA doesn't change, the test results can be used to guide medication and dosage decisions for years to come.

Tools and reports for providers

With the RightMed comprehensive test, providers get access to additional complimentary tools and reports.

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The RightMed Advisor

Providers also get access to the RIGHTMED ADVISOR, an interactive tool to help providers quickly and easily interpret test results, explore more information about the hundreds of medications in OneOme’s database, evaluate drug-to-drug interactions, and view curated medication alternatives.

Providers can generate custom reports by selecting the medications they would like displayed in a RightMed Advisor custom report, which helps providers get more in-depth information and focus on the drugs that matter the most for each patient.

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Reports

In addition to the RightMed comprehensive test report, providers can choose to receive additional reports in order to get easy access to the most relevant information.

RightMed Advisor reports are customized reports that provide in-depth information on the medications that are most relevant to the patient. Speciality reports, including our psychiatry and oncology reports, include a subset of medications that are most relevant for a specific medical speciality.

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Sample collection and processing

The RightMed comprehensive test includes DNA collection through a cheek (buccal) swab. Alternatively, DNA can also be collected by blood. DNA samples are processed at OneOme’s in-house CLIA/CAP-accredited laboratory.

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UPDATES FROM ONEOME

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TEST REQUISITION FORM

Complete a simple test requisition form to place your first order.

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PROVIDER TOOLKIT

Get more information, plus the tools you need to get started.

Are you a patient? LEARN HOW TO GET THE RIGHTMED TEST >

This test is not right for everyone. Consult your doctor to see if this test is right for you.

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The RightMed Advisor

Providers also get access to the RIGHTMED ADVISOR, an interactive tool to help providers quickly and easily interpret test results, explore more information about the hundreds of medications in OneOme’s database, evaluate drug-to-drug interactions, and view curated medication alternatives.

Providers can generate custom reports by selecting the medications they would like displayed in a RightMed Advisor custom report, which helps providers get more in-depth information and focus on the drugs that matter the most for each patient.

Report icon

Reports

In addition to the RightMed comprehensive test report, providers can choose to receive additional reports in order to get easy access to the most relevant information.

RightMed Advisor reports are customized reports that provide in-depth information on the medications that are most relevant to the patient. Speciality reports, including our psychiatry and oncology reports, include a subset of medications that are most relevant for a specific medical speciality.