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RightMed comprehensive test

The RightMed® comprehensive test is a provider-ordered pharmacogenomic test that analyzes a patient’s DNA to determine how he or she may respond to hundreds of medications used to treat and manage many medical conditions. With the help of the RightMed tools and services, providers can identify which medications may — or may not — work best for the patient. This may lead to more effective prescriptions, fewer side effects, and less trial and error to find the right medication.

Test details

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The RightMed comprehensive test covers hundreds of commonly prescribed medications, including omeprazole (Prilosec), simvastatin (Zocor), citalopram (Celexa), clopidogrel (Plavix), warfarin (Coumadin), codeine, morphine, alprazolam (Xanax), phenytoin (Dilantin), metoprolol (Lopressor), plus many more.

View complete medication list >

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The RightMed comprehensive test covers medications used for many medical conditions.

    • Acute migraine
    • ADHD
    • Allergies
    • Alzheimer's disease
    • Anticoagulation
    • Antiplatelet therapy
    • Anxiety
    • Arrhythmias
    • Bacterial infection
    • Benign prostatic
    • Cancer
    • Chronic hepatitis C
    • Depression
    • Diabetes
    • Dyslipidemia
    • Fungal infection
    • Gastroesophageal
      reflux disease
    • Gout
    • HIV infection
    • Hypertension
    • Immunosuppression
    • Migraine prophylaxis
    • Overactive bladder
    • Pain
    • Parkinson's disease
    • Psychosis
    • Rheumatoid arthritis
    • Seizures
    • Sleep disorders
    • Smoking cessation

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The RightMed comprehensive test analyzes genes involved in drug metabolism, drug targets, drug receptors, and drug transporters. Analysis is provided for genes that have been shown, based on OneOme's rigorous research and standards for inclusion, to affect how a patient responds to many commonly prescribed medications.

CYP1A2 *1C, *1D, *1E, *1F, *1J, *1K, *1L, *1V, *1W Toggle icon

rs12720461 NM_000761.4:c.-10+113C>T

rs2069514 NG_008431.2:g.28338G>A

rs2069526 NM_000761.4:c.-10+103T>G

rs35694136 NM_000761.4:c.-1635delT

rs762551 NM_000761.4:c.-9-154C>A

CYP2B6 *4, *5, *6, *7, *9, *16, *18 Toggle icon

rs2279343 NM_000767.4:c.785A>G

rs28399499 NM_000767.4:c.983T>C

rs3211371 NM_000767.4:c.1459C>T

rs3745274 NM_000767.4:c.516G>T

CYP2C Cluster G/A Toggle icon

rs12777823 NC_000010.10:g.96405502G>A

CYP2C9 *2, *3, *4, *5, *6, *8, *11, *18 Toggle icon

rs1057910 NM_000771.3:c.1075A>C

rs1057911 NM_000771.3:c.1425A>T

rs1799853 NM_000771.3:c.430C>T

rs28371685 NM_000771.3:c.1003C>T

rs28371686 NM_000771.3:c.1080C>G

rs56165452 NM_000771.3:c.1076T>C

rs7900194 NM_000771.3:c.449G>A

rs9332131 NM_000771.3:c.817delA

CYP2C19 *2, *3, *4, *4B, *10, *17 Toggle icon

rs12248560 NM_000769.2:c.-806C>T

rs28399504 NM_000769.2:c.1A>G

rs4244285 NM_000769.2:c.681G>A

rs4986893 NM_000769.2:c.636G>A

rs6413438 NM_000769.2:c.680C>T

CYP2D6 *2A, *2, *3, *4, *4N, *4M, *5, *6, *6C, *7, *8, *9, *10, *11, *12, *13, *14A, *14B, *15, *17, *18, *19, *29, *31, *34, *35, *36, *39, *41, *42, *59, *63, *64, *68, *69, *70, *91, *109 Toggle icon

hCV32407220 (rs765776661) NM_000106.5:c.1411_1412insTGCCCACTG

rs1065852 NM_000106.5:c.100C>T

rs1080985 NM_000106.5:c.-1584C>G

rs1135840 NM_000106.5:c.1457G>C

rs16947 NM_000106.5:c.886C>T

rs201377835 NM_000106.5:c.181-1G>C

rs267608319 NM_000106.5:c.1319G>A

rs28371706 NM_000106.5:c.320C>T

rs28371725 NM_000106.5:c.985+39G>A

rs35742686 NM_000106.5:c.775delA

rs3892097 NM_000106.5:c.506-1G>A

rs5030655 NM_000106.5:c.454delT

rs5030656 NM_000106.5:c.841_843delAAG

rs5030862 NM_000106.5:c.124G>A

rs5030865 NM_000106.5:c.505G>A

rs5030867 NM_000106.5:c.971A>C

rs59421388 NM_000106.5:c.1012G>A

rs72549346 NM_000106.5:c.1088_1089insGT

rs72549353 NM_000106.5:c.765_768delAACT

rs769258 NM_000106.5:c.31G>A

rs774671100 NM_000106.5:c.137_138insT

rs79292917 NM_000106.5:c.975G>A

CYP3A4 *1B, *22 Toggle icon

rs2740574 NM_017460.5:c.-392G>A

rs35599367 NM_017460.5:c.522-191C>T

CYP3A5 *3, *6, *7 Toggle icon

rs10264272 NM_000777.4:c.624G>A

rs41303343 NM_000777.4:c.1035_1036insT

rs776746 NM_000777.4:c.219-237G>A

CYP4F2 *3 Toggle icon

rs2108622 NM_001082.4:c.1297G>A

COMT Val158Met Toggle icon

rs4680 NM_000754.3:c.472G>A

DPYD *2A (1905+1G>A, IVS14+1G>A), Asp949Val, *13 Toggle icon

rs3918290 NM_000110.3:c.1905+1G>A

rs55886062 NM_000110.3:c.1679T>G

rs67376798 NM_000110.3:c.2846A>T

DRD2 Promoter variant -241A>G Toggle icon

rs1799978 NM_000795.3:c.-585A>G

F2 20210G>A Toggle icon

rs1799963 NM_000506.4:c.*97G>A

F5 Arg534Gln (Leiden, 1691G>A) Toggle icon

rs6025 NM_000130.4:c.1601G>A

GRIK4 Non-coding (intronic) T>C variant Toggle icon

rs1954787 NM_001282470.2:c.83-10039T>C

HLA-A HLA-A*31:01 Toggle icon

HLA00097 NM_002116 (interrogated at exon 2)

HLA-B HLA-B*15:02, HLA-B*57:01, HLA-B*58:01 Toggle icon

HLA00386 NM_005514 (interrogated at exon 2 and intron 2)

HLA00381 NM_005514 (interrogated at exon 3)

rs144012689 NM_005514.7:c.1012+104A>T

HTR2A Intron 2, T>C variant Toggle icon

rs7997012 NM_000621.4:c.614-2211T>C

HTR2C Promoter variant -759C>T Toggle icon

rs3813929 NM_000868.3:c.-759C>T

IL28B (IFNL4) Non-coding (intronic) C>T variant Toggle icon

rs12979860 NM_001276254.2:c.151-152G>A

MTHFR 677C>T; 1298A>C Toggle icon

rs1801133 NM_005957.4:c.665C>T

rs1801131 NM_005957.4:c.1286A>C

NUDT15 Arg139Cys Toggle icon

rs116855232 NM_018283.3:c.415C>T

OPRM1 Asn40Asp; 118A>G Toggle icon

rs1799971 NM_000914.4:c.118A>G

SLC6A4 c.-1810A>G; -1791_-1749del43 Toggle icon

rs25531 NM_001045.5:c-1936A>G

rs774676466 NM_001045.5:c.-1917_-1875del43

SLCO1B1 *5, *17, *21 Toggle icon

rs4149015 NM_006446.4:c.-910G>A

rs4149056 NM_006446.4:c.521T>C

rs2306283 NM_006446.4:c.388A>G

TPMT *2, *3A, *3B, *3C, *4 Toggle icon

rs1142345 NM_000367.3:c.719A>G

rs1800460 NM_000367.3:c.460G>A

rs1800462 NM_000367.3:c.238G>C

rs1800584 NM_000367.3:c.626-1G>A

UGT1A1 *6, *28 (TA7) Toggle icon

rs1976391 NM_001072.3:c.862-9697A>G

rs4148323 NM_001072.3:c.862-6536G>A

VKORC1 Promoter variant -1639G>A Toggle icon

rs9923231 NM_001311311.1:c.-1639G>A

rs7200749 NM_001311311.1:c.442C>T

MTHFR is available as optional, complimentary add-on to the RightMed comprehensive test.

Learn more about these genes, including their impact on medication response and any guidelines associated with them.

RightMed comprehensive test report

Test results are presented in the RightMed comprehensive test report, which categorizes medications into a simple, easy-to-read format:

  • high risk icon

  • medium risk icon

  • low risk icon

Given that a patient's DNA doesn't change, the test results can be used to guide medication and dosage decisions for years to come.

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The RightMed Advisor

Providers also get access to the RIGHTMED ADVISOR, an interactive tool to help providers quickly and easily interpret test results, explore more information about the hundreds of medications in OneOme’s database, evaluate drug-to-drug interactions, and view curated medication alternatives.

Providers can generate custom reports by selecting the medications they would like displayed in a RightMed Advisor custom report, which helps providers get more in-depth information and focus on the drugs that matter the most for each patient.

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In addition to the RightMed comprehensive test report, providers can choose to receive additional reports in order to get easy access to the most relevant information.

RightMed Advisor reports are customized reports that provide in-depth information on the medications that are most relevant to the patient. Speciality reports, including our psychiatry and oncology reports, include a subset of medications that are most relevant for a specific medical speciality.

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Sample collection and processing

The RightMed comprehensive test includes DNA collection through either buccal (cheek) swab or blood. DNA samples are processed at OneOme’s in-house CLIA/CAP-accredited laboratory.

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Get more information, plus the tools you need to get started.

If you are a patient, learn more about the RightMed test and how to get it by downloading our PATIENT TOOLKIT.

This test is not right for everyone. Consult your doctor to see if this test is right for you.